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Disorders of neuromuscular transmission in infants and children
Author(s) -
Cornblath David R.
Publication year - 1986
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880090705
Subject(s) - neuromuscular transmission , medicine , physical medicine and rehabilitation , pediatrics , anesthesia
Disorders of neuromuscular transmission in infants and children can be divided into two groups. The first group includes conditions similar to those seen in adults: autoimmune myasthenia gravis, Lambert‐Eaton myasthenic syndrome, and botulism. The second includes several disorders that are unique to this age group, such as the congenital myasthenias and infantile botulism. This review discusses the diseases of neuromuscular transmission found in the pediatric population, with emphasis on electrodiagnosis. The distinctive clinical and electrophysiologic features allow the clinician to identify these illnesses correctly, so that appropriate treatment can be instituted or further specialized investigation can be undertaken.