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The amino acid sequence of human cardiac troponin‐C
Author(s) -
Roher Alex,
Lieska Norman,
Spitz Werner
Publication year - 1986
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880090112
Subject(s) - edman degradation , peptide sequence , troponin c , amino acid , sequence (biology) , troponin , troponin t , amino acid residue , biochemistry , chemistry , troponin i , biology , medicine , gene , myocardial infarction
The amino acid sequence of human cardiac troponin‐C (TN‐C) has been rabbit cardiac TN‐C. These results show that troponin‐C is one of the Edman degradation. The sequence, which consists of 161 amino acid residues is identical to that of the ox heart and as such is capable of binding three calcium ions. It differs at only one position from that of rabbit cardiac TN‐C. These results show that troponin C is one of the most highly conserved proteins known.