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Multiple sclerosis and hypertrophic demyelinating peripheral neuropathy
Author(s) -
Il Ro Young,
Alexander C. Bruce,
Oh Shin J.
Publication year - 1983
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880060411
Subject(s) - medicine , peripheral neuropathy , sural nerve , multiple sclerosis , nerve conduction , nerve biopsy , biopsy , pathology , surgery , immunology , diabetes mellitus , endocrinology
A combination of multiple sclerosis (MS) and hypertrophic demyelinating neuropathy has been reported in a few autopsy studies. We are reporting a unique case of such a combination, which was proved by the sural nerve biopsy. A patient with classical MS on history and findings had areflexia and sensory abnormalities in stocking distribution. The nerve conduction study showed marked abnormalities indicative of demyelinating neuropathy, and sural nerve biopsy was typical of hypertrophic demyelinating neuropathy.