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Nonviral intranuclear inclusions in a nerve biopsy: An ultrastructural study
Author(s) -
Vallat J. M.,
Leboutet M. J.,
Loubet A.,
Corvisier N.,
Dumas M.
Publication year - 1983
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880060215
Subject(s) - ultrastructure , pathology , medicine , anatomy , biopsy
During the ultrastructural study of a nerve biopsy from a diabetic patient suffering from chronic polyradiculoneuritis, we observed that a significant number of endoneural fibroblasts had abnormal nuclei. They contained a round, centrally located inclusion consisting of numerous irregularly arranged filaments approximately 15 nm in diameter. No such lesion in peripheral nerve has previously been reported. Interpretation of these abnormalities is difficult.