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Sodium currents in human skeletal muscle fibers
Author(s) -
Decoursey T. E.,
Bryant S. H.,
Lipicky R. J.
Publication year - 1982
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880050805
Subject(s) - sodium , skeletal muscle fibers , skeletal muscle , sodium channel , voltage clamp , intercostal muscle , biophysics , chemistry , anatomy , kinetics , membrane potential , biology , physics , organic chemistry , quantum mechanics , respiratory system
Sodium currents from human external intercostal muscle fibers were recorded using the Hille‐Campbell voltage clamp method. Sodium currents are analyzed in terms of the m and h parameters of the Hodgkin‐Huxley model. The results indicate that the kinetics and voltage dependence of sodium currents in human skeletal muscle fibers are very similar to those reported in rat fibers.