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Regeneration of peripheral nerve through a polyglactin tube
Author(s) -
Molander Hårkan,
Olsson Yngve,
Engkvist Ove,
Bowald Staffan,
Eriksson Ingvar
Publication year - 1982
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880050110
Subject(s) - tube (container) , regeneration (biology) , anatomy , peripheral nerve , bridge (graph theory) , tibial nerve , materials science , medicine , biology , composite material , stimulation , microbiology and biotechnology
Polyglactin 910, a resorbable synthetic material, was used as a mesh‐tube to bridge defects (7 to 9 mm in length) in sectioned rabbit tibial nerve. After absorption of the mesh a new nerve sheath was formed which enclosed numerous minute fascicles of regenerating axons. The polyglactin tube influenced the direction taken by the regenerating axons and guided them into the distal segment. The tube also reduced the formation of neuromas and the growth of scar tissue from surrounding structures.