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Canine muscle fiber types and susceptibility of masticatory muscles to myositis
Author(s) -
Orvis Julia Stephens,
Cardinet George H.
Publication year - 1981
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880040411
Subject(s) - myocyte , anatomy , myositis , masticatory force , biology , masseter muscle , myosin , muscle fibre , pathology , medicine , skeletal muscle , microbiology and biotechnology , orthodontics
Abstract The myofiber type composition was studied in 42 different muscles of the dog to determine if there are unique features that might explain the preferential involvement of the muscles of mastication by inflammatory myopathies. The principal myofiber types for most muscles studied were type 1 and type 2A and, to a lesser extent, type 2C, wherease the dorsal group of muscles innervated by the mandibular nerve (Mm. temporalis, masseter, pterygoideus lateralis, pterygoideus medialis, tensor tympani, and tensor veli palatini) was composed only of type 2C myofibers and a variant of the type 1 myofiber whose staining intensity was not fully reversed after preincubation in acid media. The distribution of this myofiber type composition was associated with the innervation and embryologic development of the dorsal muscles innervated by the mandibular nerve. This unique myofiber type composition could provide the basis for the preferential susceptibility of these muscles to agents (e.g., immune and/or infectious) that produce myositis; however, further studies are required to assess that possiblity.