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Physical probes of biological membranes in studies of the muscular dystrophies
Author(s) -
Barchi R. L.
Publication year - 1980
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880030109
Subject(s) - current (fluid) , computer science , nanotechnology , physics , materials science , thermodynamics
This review deals with recent physical approaches to the study of biomembranes. First, current concepts of the structure and dynamic organization of biological membranes are considered. The theoretical basis and practical application of various physical probe techniques are then discussed with specific reference to their usefulness in studies of these membranes. Particular emphasis is given to electron spin resonance and fluorescence techniques and to the potential difficulties encountered in their use and interpretation. Finally, reports applying these physical probes to various aspects of the human muscular dystrophies are reviewed and our current information in this area is summarized.