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Neural hyperexcitability in hyperkalemic periodic paralysis
Author(s) -
Segura Roberto P.,
Petajan Jack H.
Publication year - 1979
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880020402
Subject(s) - medicine , paralysis , peripheral , peripheral nerve , periodic paralysis , electromyography , anesthesia , neuroscience , anatomy , surgery , psychology , physical medicine and rehabilitation
An electrophysiologic study of peripheral nerve excitability was performed in patients with hyperkalemic periodic paralysis (HPP) and in normal controls. It was found that a marked degree of neural hyperexcitability existed in all patients with HPP who showed cold sensitivity. The results suggest involvement of the nerve cell membrane in the proximal segments of peripheral nerve. This testing method may be of value in differentiating the cold‐sensitive variant of HPP.