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Peripheral nerve responses during ischemia in the evaluation of diabetic neuropathy
Author(s) -
Horowitz Steven H.,
GinsbergFellner Fredda
Publication year - 1978
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.880010507
Subject(s) - medicine , nerve conduction velocity , ischemia , peripheral neuropathy , diabetic neuropathy , diabetes mellitus , peripheral , cardiology , nerve conduction , anesthesia , surgery , endocrinology
The stability of sensory conduction and evoked potentials during ischemia has been used in the evaluation of diabetic neuropathy and diabetic control (Hgb A 1 C). Six newly diagnosed juvenile diabetics were studied at diagnosis and 3 to 12 months later. In three patients in good control, ischemic “resistance” became normal. In three patients in poor control, resistance remained increased; two of these three experienced a 10%–20% slowing in conduction velocity. Similar relationships between control and ischemic resistance are found in long‐term diabetics. These data suggest that abnormal ischemic resistance may herald the onset of an electrical and clinical neuropathic state.