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Compound muscle action potential scan and MScanFit motor unit number estimation during Wallerian degeneration after nerve transections
Author(s) -
KesimSahin Ozlem,
Sirin Nermin Gorkem,
Erbas Bahar,
Artug Tugrul,
OguzAkarsu Emel,
KocasoyOrhan Elif,
Baslo Mehmet Baris,
Mammadova Nermin,
Emekli Ufuk,
Oge Ali Emre
Publication year - 2020
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.26923
Subject(s) - compound muscle action potential , reinnervation , wallerian degeneration , motor unit , denervation , medicine , electrophysiology , anesthesia , anatomy
Background Compound muscle action potential (CMAP) scan and MScanFit have been used to understand the consequences of denervation and reinnervation. This study aimed to monitor these parameters during Wallerian degeneration (WD) after acute nerve transections (ANT). Methods Beginning after urgent surgery, CMAP scans were recorded at 1–2 day intervals in 12 patients with ANT of the ulnar or median nerves, by stimulating the distal stump (DS). Stimulus intensities (SI), steps, returners, and MScanFit were calculated. Studies were grouped according to the examination time after ANT. Results were compared with those of 27 controls. Results CMAP amplitudes and MScanFit progressively declined, revealing a positive correlation with one another. SIs were higher in WD groups than controls. Steps appeared or disappeared in follow‐up scans. The late WD group had higher returner% than the early WD and control groups. Conclusions MScanFit can monitor neuromuscular dysfunction during WD. SIs revealed excitability changes in DS.