Premium
Diabetic polyneuropathy and the risk of developing carpal tunnel syndrome: A nationwide, population‐based study
Author(s) -
Moon Hyun Im,
Shin Jaeyong,
Kim Yong Wook,
Chang Jee Suk,
Yoon SeoYeon
Publication year - 2020
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.26901
Subject(s) - medicine , carpal tunnel syndrome , hazard ratio , confidence interval , proportional hazards model , polyneuropathy , logistic regression , diabetes mellitus , population , national health insurance , surgery , endocrinology , environmental health
Background We investigated the risk of carpal tunnel syndrome (CTS) in diabetic polyneuropathy (DPN). Methods This study was conducted using records from the National Health Insurance System (NHIS). We divided patients diagnosed with diabetes mellitus (DM) into those with and without DPN. We assessed the effect of DPN on the risk of CTS using Cox proportional hazards regression analyses. Results DPN was associated with an increased risk of CTS (hazard ratio [HR], 1.33; 95% confidence interval [CI], 1.12–1.58). In sub‐analyses, female gender (HR, 1.45; 95% CI, 1.20–1.76), presence of type 2 DM (HR, 1.36; 95% CI, 1.11–1.64), and age 35 to 64 years (HR 1.35; 95% CI, 1.11–1.64) were significantly associated with an increased risk of CTS. Conclusions Patients with DPN had an increased risk of CTS compared with the non‐DPN group, particularly females, those with type 2 DM, and those aged 35 to 64 years.