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7T MR neurography‐ultrasound fusion for peripheral nerve imaging
Author(s) -
Schreiber Stefanie,
Schreiber Frank,
Peter Alica,
Isler Eser,
Dörner Marc,
Heinze HansJochen,
Petri Suanne,
Tempelmann Claus,
Nestor Peter J.,
Grimm Alexander,
Vielhaber Stefan
Publication year - 2020
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.26800
Subject(s) - magnetic resonance neurography , medicine , polyradiculoneuropathy , peripheral , ultrasound , peripheral nervous system , peripheral nerve , radiology , pathology , guillain barre syndrome , central nervous system , magnetic resonance imaging , anatomy , immunology
Background We present one patient with an initial diagnosis of Guillain‐Barré syndrome (GBS) and one with Charcot–Marie–Tooth disease (CMT) type 1A. Methods Both patients underwent ankle tibial nerve fusion‐imaging of high‐resolution ultrasound (HRUS) with 7T MR neurography (MRN). Results In GBS, the nerve was enlarged, T2‐hyperintense, and showed increased vascularization 21 months after symptom onset. In CMT1A, the enlarged nerve was T2‐isointense with normal endoneurial blood flow. Conclusions We demonstrate the utility of 7T‐MRN‐HRUS‐fusion‐imaging. In GBS, there was evidence of ongoing inflammation resulting in a changed diagnosis to acute‐onset chronic demyelinating polyradiculoneuropathy and maintenance of immunotherapy. By MRN‐HRUS‐fusion, patients with presumed peripheral axonal degeneration could be shown to display imaging markers associated with peripheral nervous system inflammation. Thus, more accurate identification of a treatable inflammatory component may become possible.