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Reproducibility of motor unit number index and multiple point stimulation motor unit number estimation in controls
Author(s) -
Higashihara Mana,
Me Parvathi,
Bos Mehdi,
Geevasinga Nimeshan,
Vucic Steve
Publication year - 2018
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.26339
Subject(s) - reproducibility , intraclass correlation , medicine , motor unit , coefficient of variation , anatomy , mathematics , statistics
: Reproducibility of the multiple point stimulation motor unit number estimation (MPS‐MUNE) technique was compared with the recently developed motor unit number index (MUNIX) technique. Methods : MPS‐MUNE and MUNIX were performed on 15 healthy subjects at 3 different time‐points by the same examiner. Reproducibility was analyzed using intraclass correlation coefficient (ICC) and coefficient of variation (CV). Results : ICC values for MUNIX and MPS‐MUNE were excellent across 3 tests (0.80 and 0.77, respectively), although CV values were significantly lower for MUNIX than MPS‐MUNE ( P < 0.01). In addition, test‐retest reproducibility was better for MUNIX, a finding largely attributable to poor reproducibility of the single motor unit action potential area. MUNIX ( R = −0.48, P < 0.05) and MPS‐MUNE ( R = −0.53, P < 0.05) were significantly correlated with age. Discussion : MUNIX demonstrated better intrarater reproducibility and may be a more reliable neurophysiological biomarker than MPS‐MUNE. Muscle Nerve 58 : 660–664, 2018