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Translation, cross‐cultural adaptation, and validation of the chinese version of the 15‐item myasthenia gravis quality of life questionnaire
Author(s) -
Miao Xiaohui,
Lian Zhiyun,
Liu Ju,
Chen Hongxi,
Shi Ziyan,
Li Mier,
Zhou Hongyu,
Hu Xiuying,
Yang Rong
Publication year - 2019
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.26313
Subject(s) - cronbach's alpha , myasthenia gravis , construct validity , discriminant validity , concurrent validity , quality of life (healthcare) , psychology , physical therapy , medicine , clinical psychology , psychometrics , internal consistency , psychotherapist
: We sought to translate, cross‐culturally adapt, and evaluate the internal consistency and validity of the Chinese version of the 15‐Item Myasthenia Gravis Quality of Life (MG‐QOL15). Methods : Translation and cross‐cultural adaptation of the MG‐QOL15 were performed. We used Cronbach's α to test internal consistency, one‐way analysis of variance to test construct validity, and Pearson or Spearman correlations to test discriminant and concurrent validity. Results : We enrolled 168 outpatients. Internal consistency was excellent (Cronbach's α = 0.928). The MG‐QOL15 discriminated MG severity as stratified by the MG Composite (MGC; P < 0.001) and Osserman class ( P = 0.01). Concurrent validity was low to moderate with the subscales of the 36‐item Short Form (−0.31 to ∼−0.59), MGC ( r = 0.46), and Myasthenia Gravis Activities of Daily Living profile ( r = 0.54). Discussion : The Chinese MG‐QOL15 showed comparable construct, discriminant and concurrent validity, and internal consistency with to the original version. Muscle Nerve 59 :95–99, 2019