Translation, cross‐cultural adaptation, and validation of the chinese version of the 15‐item myasthenia gravis quality of life questionnaire

: We sought to translate, cross‐culturally adapt, and evaluate the internal consistency and validity of the Chinese version of the 15‐Item Myasthenia Gravis Quality of Life (MG‐QOL15). Methods : Translation and cross‐cultural adaptation of the MG‐QOL15 were performed. We used Cronbach's α to test internal consistency, one‐way analysis of variance to test construct validity, and Pearson or Spearman correlations to test discriminant and concurrent validity. Results : We enrolled 168 outpatients. Internal consistency was excellent (Cronbach's α = 0.928). The MG‐QOL15 discriminated MG severity as stratified by the MG Composite (MGC; P  < 0.001) and Osserman class ( P  = 0.01). Concurrent validity was low to moderate with the subscales of the 36‐item Short Form (−0.31 to ∼−0.59), MGC ( r  = 0.46), and Myasthenia Gravis Activities of Daily Living profile ( r  = 0.54). Discussion : The Chinese MG‐QOL15 showed comparable construct, discriminant and concurrent validity, and internal consistency with to the original version. Muscle Nerve 59 :95–99, 2019