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Autoimmune antibodies to collagen XIII in myasthenia gravis patients
Author(s) -
Tu Hongmin,
PirskanenMatell Ritva,
Heikkinen Anne,
Oikarainen Tuomo,
Risteli Juha,
Pihlajaniemi Taina
Publication year - 2018
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.25969
Subject(s) - myasthenia gravis , medicine , high resolution , magnetic resonance neurography , peripheral nerve , low resolution , anatomy , magnetic resonance imaging , pathology , radiology , remote sensing , geology
: Evaluation of the nerve fascicular structure can be useful in diagnosing nerve damage, but it is a very challenging task with 3T MRI because of limited resolution. In this pilot study, we present the feasibility of high‐resolution 7T MRI for examining the nerve fascicular structure. Methods : A 3‐dimensional (3D) gradient‐spoiled sequence was used for imaging peripheral nerves in extremities. Images acquired with different in‐plane resolutions (0.42 × 0.42 mm vs. 0.12 × 0.12 mm), and different main field strengths (7T vs. 3T) were compared. Results : The individual nerve fascicles were identified at 0.12 × 0.12 mm resolution in both field strengths but not at 0.42 × 0.42 mm resolution. The fascicular structure was more sharply depicted in 7T images than in 3T images. Discussion : High‐resolution 3D imaging with 7T MRI demonstrated feasibility for imaging nerve fascicular structures. Muscle Nerve 57 : 506–510, 2018