Premium
An instrumented timed up and go in facioscapulohumeral muscular dystrophy
Author(s) -
Huisinga Jessie,
Bruetsch Adam,
Mccalley Ayla,
Currence Melissa,
Herbelin Laura,
Jawdat Omar,
Pasnoor Mamatha,
Dimachkie Mazen,
Barohn Richard,
Statland Jeffrey
Publication year - 2018
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.25955
Subject(s) - facioscapulohumeral muscular dystrophy , physical medicine and rehabilitation , intraclass correlation , medicine , gait , muscular dystrophy , physical therapy , psychometrics , clinical psychology
: Instrumenting timed functional motor tasks may reveal a continuum of motor disability that predicts future motor dysfunction. Methods : We performed a prospective study of the instrumented timed up and go (iTUG) test in genetically confirmed facioscapulohumeral muscular dystrophy (FSHD) participants using a commercially available system of wireless motion sensors. Patients returned within 2 weeks to determine test–retest reliability. Gait parameters in FSHD participants were compared with a normative database, FSHD clinical severity score, manual muscle testing, and patient‐reported functional disability. Results : Gait parameters in FSHD participants were significantly ( P < 0.05) altered compared with normative values, and reliability was excellent (intraclass correlation coefficient 0.84–0.99). Stride velocity and trunk sagittal range of motion had moderate to strong correlations to other FSHD disease measures. Discussion : The iTUG was reliable, abnormal in FSHD, and could distinguish between participants with differing disease severities. Instrumenting timed functional tasks may prove to be useful in FSHD clinical trials. Muscle Nerve 57 : 503–506, 2018