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Age may contribute to the increased frequency of axonal Guillain‐Barré syndrome
Author(s) -
Hawkes Maximiliano A.,
Wilken Miguel,
Vázquez Gabriel,
Farez Mauricio F.
Publication year - 2017
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.25679
Subject(s) - guillain barre syndrome , acute motor axonal neuropathy , medicine , pediatrics , cohort , retrospective cohort study , axonal degeneration , cohort study , pathology
The frequency of axonal Guillain‐Barré syndrome (GBS) varies among countries. Previous studies supporting the high frequency of axonal GBS in South America have been carried out with pediatric populations. We seek to determine the frequency of axonal GBS in both children and adults in South America. Methods This is a retrospective cohort analysis of patients who were diagnosed with GBS between January 2006 and December 2013 in a neurological center in Buenos Aires, Argentina. Adults and children with a diagnosis of GBS were included and classified by applying Ho and colleagues' criteria 1 for axonal GBS. Results The study included 105 patients with GBS. Among 58 adults, only 5 individuals were classified as axonal GBS compared with 16 of 47 children. The frequency of axonal GBS was significantly higher in children than in adults (34% vs. 8.6%, P = 0.0001). Discussion As shown in a cohort of South American patients, age may impact the frequency of axonal GBS. Muscle Nerve 56 : 1311–1313, 2017