Cross‐education after high‐frequency versus low‐frequency volume‐matched handgrip training

: Cross‐education training programs cause interlimb asymmetry of strength and hypertrophy. We examined the cross‐education effects from a high‐frequency (HF) versus a low‐frequency (LF) volume‐matched handgrip training program on interlimb asymmetry. Methods : Right‐handed participants completed either HF ( n = 10; 2 × 6 repetitions 10 times per week) or LF ( n = 9; 5 × 8 repetitions 3 times per week) training. Testing occurred twice before and once after 4 weeks of right‐handed isometric handgrip training totaling 120 weekly repetitions. Measures were maximal isometric handgrip and wrist flexion torque, muscle thickness, and muscle activation (electromyography; EMG). Results : Grip strength was greater in both limbs posttraining, pooled across groups ( P < 0.001). Trained limb muscle thickness increased in both groups ( P < 0.05; untrained, P = 0.897). EMG and wrist flexion torque did not change (all P > 0.103). Discussion : Both LF and HF induced cross‐education of grip strength to the untrained limb, but HF did not reduce asymmetry. These findings have implications for injury rehabilitation. Muscle Nerve 56 : 689–695, 2017