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Single‐fiber EMG with concentric electrodes in lambert‐eaton myasthenia
Author(s) -
Guan Yuzhou,
Ding Qingyun,
Liu Mingsheng,
Niu Jingwen,
Cui Liying
Publication year - 2017
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.25500
Subject(s) - repetitive nerve stimulation , neuromuscular transmission , medicine , electromyography , concentric , compound muscle action potential , myasthenia gravis , jitter , anatomy , electrophysiology , anesthesia , physical medicine and rehabilitation , mathematics , geometry , electronic engineering , engineering
: We analyzed jitter recordings made with concentric needle electrode (CNE) single‐fiber electromyography (SFEMG) in Lambert‐Eaton myasthenia (LEM). Methods : Fifteen subjects diagnosed with LEM were studied using CNE‐SFEMG in the extensor digitorum (ED) and tibialis anterior (TA) muscles. CNE‐SFEMG in the ED and TA was also used to evaluate 12 and 10 healthy controls (HCs), respectively. Results : Ten men and 5 women were diagnosed with LEM based on an increase of 100% in compound muscle action potential amplitude during 50 H z repetitive nerve stimulation. All patients exhibited markedly greater jitter in the ED (88.8 ± 23.2 µs) and TA (92.2 ± 30.2 µs) than HCs (28.3 ± 3.4 µs and 30.9 ± 5.1 µs, respectively). Conclusions : CNE‐SFEMG is sensitive for discovering abnormalities in neuromuscular transmission in LEM. Muscle Nerve 56 : 253–257, 2017