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Double peak sensory nerve action potentials to single stimuli in nerve conduction studies
Author(s) -
Leote Joao,
Pereira Pedro,
VallsSole Josep
Publication year - 2017
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.25486
Subject(s) - neuroscience , neurophysiology , sensory system , stimulation , sensory nerve , median nerve , nerve conduction , sensory stimulation therapy , clinical neurophysiology , medicine , psychology , anatomy , surgery , electroencephalography
ABSTRACT Introduction In humans, sensory nerve action potentials (SNAPs) can show 2 separate deflections, i.e., double peak potentials (DPp), which necessarily means that 1 peak is delayed with respect to the other. DPps may have various origins and be due to either physical or physiological properties. Methods We review the nature of commonly encountered DPps in clinical practice, provide the most likely interpretations for their physiological origin, and assess their reproducibility and clinical utility. Results We classified the DPps into 3 categories: (1) simultaneous anodal and cathodal stimulation. (2) simultaneous recording from 2 different nerves at the same site, and (3) SNAP desynchronization. Conclusions Although the recording of DPps is not a standardized neurophysiological method, their study brings interesting cues about the physiology of nerve stimulation and paves the way for clinical application of such an observation. Muscle Nerve 55: 619–625, 2017