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Postural tremor and chronic inflammatory demyelinating polyneuropathy
Author(s) -
Cao Yiming,
Me Parvathi,
ChingFen Chang Florence,
Mahant Neil,
Geevasinga Nimeshan,
Fung Victor S.C.,
Vucic Steve
Publication year - 2017
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.25253
Subject(s) - chronic inflammatory demyelinating polyneuropathy , medicine , physical medicine and rehabilitation , polyradiculoneuropathy , electromyography , physical therapy , polyneuropathy , guillain barre syndrome , pediatrics , antibody , immunology
Chronic inflammatory demyelinating polyneuropathy (CIDP) typically presents with a combination of sensory and motor impairments. Tremor is recognized as a common and debilitating feature in CIDP, although the underlying mechanisms are unclear. Methods Clinical tremor severity and disability scores were collected prospectively in 25 CIDP patients and compared with 22 neuromuscular controls. Results Postural and kinetic tremor were significantly more frequent in CIDP patients (80%) than in neuromuscular controls (35%; P < 0.005). Tremor severity and tremor‐related disability were also significantly greater in CIDP patients than in controls. Accelerometry data confirmed the presence of a 5.5 Hz postural tremor and a 5 Hz kinetic tremor. Conclusions Tremor appears to be a common clinical feature of CIDP that results in significant disability. Sensory and motor impairment may be associated with development of tremor in CIDP. Muscle Nerve 55 : 338–343, 2017