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Proximal conduction block in the pharyngeal–cervical–brachial variant of guillain–barrÉ syndrome
Author(s) -
Taieb Guillaume,
Grapperon AudeMarie,
Duclos Yann,
Franques Jérôme,
Labauge Pierre,
Renard Dimitri,
Yuki Nobuhiro,
Attarian Shahram
Publication year - 2015
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.24729
Subject(s) - medicine , guillain barre syndrome , nerve conduction , nerve conduction study , plasmapheresis , median nerve , f wave , anatomy , surgery , nerve conduction velocity , immunology , antibody
Conduction block (CB) has been included in the Rajabally criteria for axonal Guillain–Barré syndrome (GBS). Because the nerve roots may be affected early in GBS, detection of proximal CB by the triple stimulation technique (TST) can be useful. Methods: We describe TST findings in 2 patients who presented with the pharyngeal–cervical–brachial (PCB) variant of axonal GBS. Results: In the first patient, although conventional nerve conduction studies (NCS) did not fit electrodiagnostic criteria for axonal GBS, the TST detected proximal CB in the median and ulnar nerves. In the second patient, NCS fulfilled criteria for axonal GBS, and the TST detected proximal CB in the median nerve. After plasmapheresis, NCS and TST findings were normalized, suggesting reversible conduction failure rather than demyelinating CB. Conclusion: The TST may be useful for diagnosis of PCB when NCS remain inconclusive. The technique provides additional clues for classifying PCB into the acute nodo‐paranodopathies. Muscle Nerve 52 : 1102–1106, 2015