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Delayed facial weakness in Guillain‐Barré and miller fisher syndromes
Author(s) -
Tatsumoto Muneto,
Misawa Sonoko,
Kokubun Norito,
Sekiguchi Yukari,
Hirata Koichi,
Kuwabara Satoshi,
Yuki Nobuhiro
Publication year - 2015
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.24475
Subject(s) - weakness , guillain barre syndrome , facial weakness , medicine , miller fisher syndrome , ataxia , muscle weakness , palsy , facial nerve , facial paralysis , facial muscles , pediatrics , surgery , pathology , anatomy , psychiatry , alternative medicine
ABSTRACT Introduction : Dr. C. Miller Fisher described the appearance of unilateral facial palsy after resolution of ataxia in a patient with the eponymic Miller Fisher syndrome (MFS). However, there have been very few reports of delayed appearance of facial weakness in Guillain‐Barré syndrome (GBS) and MFS when the other neurological signs reached nadir or started improving. Methods : In this study we reviewed the clinical and laboratory findings of consecutive patients with GBS ( n = 195) and MFS ( n = 68). Results : Delayed facial weakness occurred in 12 (6%) GBS and 4 (6%) MFS patients and was unilateral in 5 (42%) GBS and 2 (50%) MFS patients. In those patients with delayed facial weakness, neither limb weakness nor ataxia progressed, and facial weakness disappeared without immunotherapy. Conclusions : Because facial weakness can lead to further morbidity, it would be prudent for clinicians to warn patients of this possibility, although additional immunotherapy is usually not required. Muscle Nerve 51 : 811–814, 2015