Premium
Quantitative muscle ultrasound and quadriceps strength in patients with post‐polio syndrome
Author(s) -
Bickerstaffe Alice,
Beelen Anita,
Zwarts Machiel J.,
Nollet Frans,
Dijk Johannes P.
Publication year - 2015
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.24272
Subject(s) - isometric exercise , medicine , ultrasound , intensity (physics) , muscle strength , skeletal muscle , muscle weakness , quadriceps muscle , physical medicine and rehabilitation , radiology , physics , quantum mechanics
: We investigated whether muscle ultrasound can distinguish muscles affected by post‐polio syndrome (PPS) from healthy muscles and whether severity of ultrasound abnormalities is associated with muscle strength. Methods : Echo intensity, muscle thickness, and isometric strength of the quadriceps muscles were measured in 48 patients with PPS and 12 healthy controls. Results : Patients with PPS had significantly higher echo intensity and lower muscle thickness than healthy controls. In patients, both echo intensity and muscle thickness were associated independently with muscle strength. A combined measure of echo intensity and muscle thickness was more strongly related to muscle strength than either parameter alone. Conclusions : Quantitative ultrasound distinguishes healthy muscles from those affected by PPS, and measures of muscle quality and quantity are associated with muscle strength. Hence, ultrasound could be a useful tool for assessing disease severity and monitoring changes resulting from disease progression or clinical intervention in patients with PPS. Muscle Nerve 51 : 24–29, 2015