Small nerve fiber involvement in patients referred for fibromyalgia | Zendy

Giannoccaro Maria Pia | Zendy; Donadio Vincenzo | Zendy; Incensi Alex | Zendy; Avoni Patrizia | Zendy; Liguori Rocco | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Small nerve fiber involvement in patients referred for fibromyalgia

Author(s) -

Giannoccaro Maria Pia,

Donadio Vincenzo,

Incensi Alex,

Avoni Patrizia,

Liguori Rocco

Publication year - 2014

Publication title -

muscle and nerve

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.025

H-Index - 145

eISSN - 1097-4598

pISSN - 0148-639X

DOI - 10.1002/mus.24156

Subject(s) - fibromyalgia , medicine , skin biopsy , nerve fiber , neuropathic pain , thigh , cholinergic fibers , biopsy , cholinergic , surgery , anesthesia , anatomy , cholinergic neuron

: Fibromyalgia (FM) is a chronic syndrome characterized by widespread pain often accompanied by other symptoms suggestive of neuropathic pain. We evaluated patients for small fiber neuropathy (SFN) who were referred for fibromyalgia (FM). Methods : We studied 20 consecutive subjects with primary FM. Patients underwent neurological examination, nerve conduction studies, and skin biopsies from distal leg and thigh. Results : Electrodiagnostic studies were normal in all patients. SFN was diagnosed in 6 patients by reduced epidermal nerve fiber density. These patients also showed abnormalities of both adrenergic and cholinergic fibers. Conclusions : A subset of FM subjects have SFN, which may contribute to their sensory and autonomic symptoms. Skin biopsy should be considered in the diagnostic work‐up of FM. Muscle Nerve 49 : 757–759, 2014

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research