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Value of short exercise and short exercise with cooling tests in the diagnosis of myotonic dystrophies (DM1 AND DM2)
Author(s) -
Gawel Malgorzata,
SzmidtSalkowska Elzbieta,
Lusakowska Anna,
Nojszewska Monika,
Sulek Anna,
Krysa Wioletta,
Rajkiewicz Marta,
Seroka Andrzej,
Kaminska Anna M.
Publication year - 2014
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.23908
Subject(s) - myotonic dystrophy , electromyography , physical medicine and rehabilitation , compound muscle action potential , medicine , physical therapy , set (abstract data type) , muscular dystrophy , audiology , computer science , electrophysiology , programming language
: Standard electromyography (EMG) is useful in the diagnosis of myotonic dystrophy type 1 (DM1) and type 2 (DM2), but it does not differentiate between them. The aim of this study was to estimate the utility of the short exercise test (SET) and short exercise test with cooling (SETC) in differentiating between DM1 and DM2. Methods : SET and SETC were performed in 32 patients with DM1 (mean age 35.8 ± 12.7 years) and 28 patients with DM2 (mean age 44.5 ± 12.5 years). Results : We observed a significant decline in compound motor action potential (CMAP) amplitude in DM1 with both SET and SETC immediately after effort. In DM2, there was no marked change in CMAP amplitude with either SET or SETC. Conclusions : SET and SETC may serve as useful tools for clinical differentiation between DM1 and DM2, and they may be used as a guide for molecular testing. Muscle Nerve 49 : 277–283, 2014