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Single‐fiber electromyography in amyotrophic lateral sclerosis and cervical spondylosis
Author(s) -
Liu Mingsheng,
Cui Liying,
Guan Yuzhou,
Li Benhong,
Du Hua
Publication year - 2013
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.23767
Subject(s) - amyotrophic lateral sclerosis , electromyography , medicine , cervical spondylosis , jitter , physical medicine and rehabilitation , pathology , disease , alternative medicine , electronic engineering , engineering
Introduction Cervical spondylosis ( CS ) is a common disease in adults and may coexist with amyotrophic lateral sclerosis ( ALS ). It is important to detect ALS coexisting with CS ( ALS ‐cs) at an early stage, especially when surgical treatment of CS is planned. Methods Single‐fiber electromyography was performed in 26 patients with ALS , 19 with ALS ‐cs, and 22 with CS . Results Mean jitter, percentage of jitter >55 μs, and percentage of impulse blocking were not statistically different between ALS and ALS ‐cs cases, but they were significantly lower in CS . Mean fiber density was not statistically different among the 3 groups. The percentage of pairs with jitter >55 μs exceeding 40% and mean jitter exceeding 55 μs had high sensitivity and specificity in the diagnosis of ALS . Conclusions Single‐fiber electromyography can supply valuable information in helping to differentiate ALS from CS . Muscle Nerve , 2013