z-logo
Premium
Muscle X‐ray attenuation is not decreased during experimental bed rest
Author(s) -
Rittweger Jörn,
Möller Klaus,
Bareille MariePierre,
Felsenberg Dieter,
Zange Jochen
Publication year - 2013
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.23644
Subject(s) - rest (music) , bed rest , attenuation , physical medicine and rehabilitation , medicine , anatomy , physics , optics
: Muscle X‐ray attenuation (MXA) in Hounsfield units (HU) is decreased in dystrophy, aging, and immobilization. We hypothesized a decrease also during bed rest (BR). Methods : Twenty‐five healthy men performed BR for 90 days, 8 of whom performed flywheel exercise 2–3 times per week. Muscle cross‐sectional area (CSA) and MXA were assessed by computed tomography. Results : In the control group, calf muscle CSA decreased during 89‐day BR by 26.6 (SD 3.8) %, while MXA increased by 1.2 HU on day 28 and almost reached baseline values on day 89. Changes were mitigated in the flywheel group for the calf ( P < 0.001). All changes were reversed within 90 days after BR. Conclusions : Results contradict the initial hypothesis. Increased intramuscular blood content, interstitial fluid space shrinkage, and reduction of intramuscular lipid stores are possible explanations for the moderate increase in MXA during the initial phase of bed rest. Muscle Nerve 47: 722–730, 2013

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here