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Shock wave treatment improves nerve regeneration in the rat
Author(s) -
Mense Siegfried,
Hoheisel Ulrich
Publication year - 2013
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.23631
Subject(s) - regeneration (biology) , lesion , medicine , shock (circulatory) , nerve injury , immunohistochemistry , anatomy , anesthesia , pathology , biology , microbiology and biotechnology
: The aims of the experiments were to: (1) determine whether low‐energy shock wave treatment accelerates the recovery of muscle sensitivity and functionality after a nerve lesion; and (2) assess the effect of shock waves on the regeneration of injured nerve fibers. Methods : After compression of a muscle nerve in rats the effects of shock wave treatment on the sequelae of the lesion were tested. In non‐anesthetized animals, pressure pain thresholds and exploratory activity were determined. The influence of the treatment on the distance of nerve regeneration was studied in immunohistochemical experiments. Results : Both behavioral and immunohistochemical data show that shock wave treatment accelerates the recovery of muscle sensitivity and functionality and promotes regeneration of injured nerve fibers. Conclusion : Treatment with focused shock waves induces an improvement of nerve regeneration in a rodent model of nerve compression. Muscle Nerve 47: 702–710, 2013