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Electrophysiological subtypes and prognosis of Guillain–Barré syndrome in Northeastern China
Author(s) -
Ye Yuqin,
Wang Keren,
Deng Fang,
Xing Yingqi
Publication year - 2013
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.23477
Subject(s) - acute motor axonal neuropathy , medicine , guillain barre syndrome , electrophysiology , sural nerve , pediatrics , surgery
Abstract Introduction: The purpose of this study was to assess the electrophysiological subtypes and prognosis of Guillain–Barré syndrome (GBS) in northeastern China. Methods: Ninety‐nine patients with GBS were recruited between 2006 and 2010 and retrospectively reviewed. Results: Sixty‐seven percent of patients had acute inflammatory demyelinating polyneuropathy (AIDP). Patients with acute motor axonal neuropathy (AMAN) had more severe symptoms at onset of GBS, and intravenous immunoglobulin (IVIg) was less effective in these patients. The prognosis may have been associated with the severity of the illness and did not differ between AMAN and AIDP patients. Abnormal motor nerve conduction studies (NCS) of the lower limbs and sensory NCS of the upper limbs with normal sural sensory nerve studies were the main electrophysiological features of AIDP. Conclusions: AIDP is the main subtype of GBS, and it has specific electrophysiological characteristics in northeastern China. The prognosis of patients with AMAN was similar to that of patients with AIDP. Moreover, IVIg was more effective in patients with AIDP. Muscle Nerve, 2013