Premium
Skin biopsy–proven flecainide‐induced neuropathy
Author(s) -
Burakgazi Ahmet Z.,
Polydefkis Michael,
Höke Ahmet
Publication year - 2012
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.22239
Subject(s) - flecainide , medicine , dermatology , skin biopsy , peripheral neuropathy , biopsy , endocrinology , diabetes mellitus , atrial fibrillation
Flecainide acetate is a classic Ic antiarrhythmic agent used to treat a variety of cardiac arrhythmias. Non‐cardiac side effects usually affect the central nervous system. Few case reports of possible flecainide‐induced peripheral neuropathy have been reported. We report this unique case in that flecainide‐induced sensory neuropathy was confirmed with skin biopsy, and subsequent improvement of neuropathy was documented with assessment of intraepidermal nerve fiber density in a repeat nerve biopsy. Muscle Nerve 45: 144–146, 2011