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Value of distal compound muscle action potential duration prolongation in acute inflammatory demyelinating polyneuropathy: A European perspective
Author(s) -
Rajabally Yusuf A.,
Nicolas Guillaume
Publication year - 2011
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21974
Subject(s) - medicine , prolongation , compound muscle action potential , chronic inflammatory demyelinating polyneuropathy , electromyography , electrodiagnosis , polyneuropathy , polyradiculoneuropathy , guillain barre syndrome , surgery , electrophysiology , physical medicine and rehabilitation , immunology , antibody
The value of distal compound muscle action potential duration (DCMAPD) has not been widely studied in acute inflammatory demyelinating polyneuropathy (AIDP) with electromyography (EMG) equipment at low‐cut filter settings <10 Hz, as used in Europe. Methods: We retrospectively reviewed the records of 40 patients with AIDP and 40 controls with axonal neuropathy, from Leicester, UK, and Angers, France. Results: The best combination of sensitivity/specificity for AIDP using DCMAPD prolongation in any one nerve was offered by cut‐offs from two other studies (sensitivity: 90% and 87.5%, respectively; specificity: 92.5% for both). Independent DCMAPD prolongation in any one nerve was better than, or equivalent to, other criteria. Conclusions: DCMAPD prolongation in any one nerve, at cut‐offs suggested by prior studies, represents a sensitive and specific marker to aid/simplify electrodiagnosis of AIDP in patients studied with EMG equipment with low‐cut filter settings of <10 Hz. Muscle Nerve, 2011