Premium
History of outcome measures for myasthenia gravis
Author(s) -
Burns Ted M.
Publication year - 2010
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21713
Subject(s) - myasthenia gravis , quality of life (healthcare) , medicine , weighting , physical therapy , physical medicine and rehabilitation , pediatrics , radiology , nursing
This review illustrates how measurements of clinical status in patients with myasthenia gravis have evolved from clinical descriptions and estimates of mortality rates to more sophisticated evaluative instruments, including numerical rating scales that measure strength, endurance, quality of life, and activities of daily living. The rationale and use of weighting and the importance of patient‐reported outcomes are also discussed. The measurement of the steroid‐sparing effect of an immunosuppressant is also reviewed. Muscle Nerve 42: 5–13, 2010