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Polyneuropathy caused by cobalt–chromium metallosis after total hip replacement
Author(s) -
Ikeda Tokuhei,
Takahashi Kazuya,
Kabata Tamon,
Sakagoshi Daigo,
Tomita Katsuro,
Yamada Masahito
Publication year - 2010
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21638
Subject(s) - metallosis , medicine , polyneuropathy , cobalt , chromium , surgery , hip arthroplasty , arthroplasty , prosthesis , hip replacement , metallurgy , materials science
Although metal intoxication after arthroplasty causes various symptoms, polyneuropathy has never been the focus of clinical investigation. We report the case of a 56‐year‐old woman with metal neuropathy. She had metallosis after hip arthroplasty with a cobalt–chromium alloy prosthesis. She developed progressive sensory disturbance, hearing loss, and hypothyroidism. Sural nerve biopsy indicated axonopathy. After exchange arthroplasty, blood levels of cobalt and chromium decreased, and her symptoms improved. Cobalt or chromium can cause axonopathy. Muscle Nerve, 2010