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Lyme disease serology in amyotrophic lateral sclerosis
Author(s) -
Qureshi Muddasir,
Bedlack Richard S.,
Cudkowicz Merit E.
Publication year - 2009
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21438
Subject(s) - amyotrophic lateral sclerosis , lyme disease , medicine , borrelia burgdorferi , serology , neuroborreliosis , disease , ceftriaxone , lyme , pathology , dermatology , immunology , antibody , antibiotics , biology , microbiology and biotechnology
Lyme disease is sometimes part of the differential diagnosis for amyotrophic lateral sclerosis (ALS). Herein we report on 414 individuals with ALS at the Massachusetts General Hospital who underwent laboratory testing for Lyme disease. Twenty‐four (5.8%) were seropositive, but only 4 (0.97%) had confirmed past immunoreactive infection. Two of these patients received ceftriaxone for 1 month without clinical improvement. Lyme disease was rare in 414 patients with ALS and is not likely to be causative. Muscle Nerve, 2009