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Dermatomyositis with inclusion body myositis pathology
Author(s) -
Layzer Robert,
Lee Han Sung,
Iverson Donald,
Margeta Marta
Publication year - 2009
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21377
Subject(s) - inclusion body myositis , dermatomyositis , myositis , medicine , prednisone , myopathy , pathology , inflammatory myopathy , methotrexate , polymyositis , inflammation , dermatology , immunology
The pathogenic role of inflammation in inclusion body myositis (IBM) remains uncertain. A 63‐year‐old man developed a severe, rapidly progressive myopathy with clinical features typical of dermatomyositis (DM), but muscle pathology was typical of IBM. Treatment with prednisone and methotrexate resulted in complete remission of symptoms. Together with two similar cases reported previously, this case suggests that the inflammatory process of DM may trigger the pathologic changes of IBM. Muscle Nerve, 2009