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Sciatic nerve moneuropathy: An unusual late effect of radiotherapy
Author(s) -
Pradat PierreFrançois,
Bouche Pierre,
Delanian Sylvie
Publication year - 2009
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21370
Subject(s) - sciatic nerve , medicine , radiation therapy , thigh , magnetic resonance imaging , mononeuropathy , trunk , anatomy , femoral nerve , nuclear medicine , radiology , peripheral neuropathy , diabetes mellitus , ecology , endocrinology , biology
In this study we report a progressive sciatic mononeuropathy occurring 13 years after radiotherapy (56‐Gy prescribed dose) for a synovial sarcoma of the thigh. Conformal dosimetric reconstitution showed that irradiation was heterogeneous and that the sciatic nerve received 66 Gy over a 25‐cm length. Magnetic resonance imaging (MRI) showed muscle fibrosis and increased sciatic nerve diameter. Our observation suggests that the risk of late mononeuropathy should be considered when large‐volume and high‐dose radiotherapy includes a nerve trunk. Muscle Nerve, 2009