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Perineuritis in acute lyme neuroborreliosis
Author(s) -
Elamin Marwa,
Alderazi Yazan,
Mullins Gerard,
Farrell Michael A.,
O'Connell Sue,
Counihan Timothy J.
Publication year - 2009
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21289
Subject(s) - medicine , mononeuritis multiplex , lyme disease , neuroborreliosis , borrelia burgdorferi , pathology , disease , immunology , vasculitis , antibody
Perineuritis is an unusual cause of direct peripheral nerve injury. We describe the clinicopathologic features of a 56‐year‐old man with mononeuritis multiplex due to Lyme disease; sural nerve biopsy demonstrated florid perineuritis. Treatment with intravenous ceftriaxone resulted in marked neurologic improvement. This study supports the notion that perineuritis forms part of the pathogenesis in acute Lyme neuroborreliosis. Muscle Nerve, 2009