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Assessment of regional body composition with dual‐energy X‐ray absorptiometry in Duchenne muscular dystrophy: Correlation of regional lean mass and quantitative strength
Author(s) -
Skalsky Andrew J.,
Han Jay J.,
Abresch Richard T.,
Shin Chris S.,
McDonald Craig M.
Publication year - 2009
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21212
Subject(s) - duchenne muscular dystrophy , lean body mass , isometric exercise , dual energy x ray absorptiometry , muscular dystrophy , muscle strength , medicine , fat mass , endocrinology , bone mineral , body weight , osteoporosis
The purpose of this study was to assess regional body composition and its correlation with regional strength in Duchenne muscular dystrophy (DMD) subjects and able‐bodied controls. Regional dual‐energy X‐ray absorptiometry (DEXA) measurements and isometric strength were obtained for 23 DMD subjects and 23 control subjects. DMD subjects showed a decreased regional lean mass ( P < 0.001). The correlation between regional strength and regional lean mass was stronger for controls than for DMD subjects. DMD subjects had decreased regional lean mass, increased regional fat mass, and decreased strength. Muscle Nerve 39: 647–651, 2009