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Response to methotrexate in a chronic inflammatory demyelinating polyradiculoneuropathy patient
Author(s) -
DíazManera Jordi,
RojasGarcía Ricard,
Gallardo Eduard,
Illa Isabel
Publication year - 2009
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.21171
Subject(s) - polyradiculoneuropathy , methotrexate , medicine , surgery , immunology , guillain barre syndrome
We report a patient with chronic inflammatory demyelinating polyradiculoneuropathy and progressive resistance to standard treatment who showed a striking response to methotrexate, 20 mg/week. The improvement, which started 5 months after initiation of therapy, was consistent and permanent. It allowed the previously wheelchair‐dependent patient to achieve pharmacological remission. The 2‐year follow‐up of this case further illustrates the role that methotrexate may play as a treatment option for CIDP patients. Muscle Nerve 39: 386–388, 2009