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Triple‐stimulation technique in multifocal neuropathy with conduction block
Author(s) -
Deroide Nicolas,
Uzenot David,
Verschueren Annie,
Azulay JeanPhilippe,
Pouget Jean,
Attarian Shahram
Publication year - 2007
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.20742
Subject(s) - medicine , multifocal motor neuropathy , nerve conduction , transcranial magnetic stimulation , nerve conduction velocity , electromyography , nerve conduction study , weakness , stimulation , anatomy , mismatch negativity , physical medicine and rehabilitation , electroencephalography , psychiatry
In patients with multifocal neuropathy with conduction block (CB), CBs located between the root and Erb's point are not detected in nerve conduction studies. We therefore examined whether the triple‐stimulation technique (TST) might provide a useful means of detecting CB proximal to Erb's point. Clinical assessments, extensive nerve conduction studies (NCS), conventional transcranial magnetic stimulation, and TST were performed on 10 patients with multifocal motor neuropathy with CB (MMNCB) and 6 patients with Lewis–Sumner syndrome. Conduction blocks located proximal to Erb's point were detected in 9 patients. Of the CBs, 58% were associated with muscle weakness. The use of TST to detect proximal CB improved the sensitivity of the American Association of Neuromuscular and Electrodiagnostic Medicine criteria for definite or probable MMNCB from 60% to 90%. Thus, the TST is a useful means for detection of proximal CB and gives NCS considerable additional diagnostic power. Muscle Nerve, 2007