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Time course of axonal regeneration in acute motor axonal neuropathy
Author(s) -
Tamura Noriko,
Kuwabara Satoshi,
Misawa Sonoko,
Kanai Kazuaki,
Nakata Miho,
Sawai Setsu,
Mori Masahiro,
Hattori Takamichi
Publication year - 2007
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.20729
Subject(s) - axonal degeneration , acute motor axonal neuropathy , regeneration (biology) , medicine , motor nerve , degeneration (medical) , neuroscience , surgery , anatomy , biology , pathology , guillain barre syndrome , pediatrics , microbiology and biotechnology
Patients with acute motor axonal neuropathy (AMAN) generally recover well. We reviewed clinical and electrophysiologic recovery in 13 patients for up to 5 years. Twelve patients showed rapid recovery over 12 months, whereas in the remaining one the recovery was slow and incomplete at 5 years. In AMAN, axonal degeneration appears to develop predominantly in the motor nerve terminals, and only occasionally more proximally in the nerve roots. Nerve terminal degeneration–regeneration presumably provides a mechanism for good recovery. Muscle Nerve, 2007