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Radiation‐induced conduction block: Resolution following anticoagulant therapy
Author(s) -
Soto Oscar
Publication year - 2005
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.20273
Subject(s) - medicine , nerve conduction , nerve conduction velocity , brachial plexopathy , pathogenesis , radiation therapy , anesthesia , surgery , brachial plexus
Neurophysiologic studies documented proximal conduction blocks in a patient harboring a delayed radiation‐induced brachial plexopathy. Since anticoagulants have been reported to be beneficial in radiation‐induced neuropathies, the patient was started on acenocumarol. After 3 months of treatment there was significant improvement of clinical deficits, which correlated with resolution of conduction blocks. This observation suggests that ischemic nerve injury leading to disruption of the conduction properties of motor axons contributes to the pathogenesis of delayed radiation‐induced peripheral nerve injuries. Muscle Nerve, 2005