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Inflammatory myopathy associated with mixed connective tissue disease and scleroderma renal crisis
Author(s) -
Greenberg Steven A.,
Amato Anthony A.
Publication year - 2001
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.1184
Subject(s) - medicine , carpal tunnel syndrome , inflammatory myopathy , connective tissue disorder , myopathy , connective tissue , connective tissue disease , dermatomyositis , scleroderma (fungus) , pathology , mixed connective tissue disease , disease , dermatology , surgery , autoimmune disease , inoculation
Mixed connective tissue disease is a rheumatological syndrome with neuromuscular manifestations that may include inflammatory myopathy and carpal tunnel syndrome. We report a patient who presented with an inflammatory myopathy and bilateral carpal tunnel syndrome prior to the diagnosis of a connective tissue disorder. Early in the course of treatment, a syndrome of acute renal failure developed. Knowledge of this syndrome, scleroderma renal crisis, and its possible relation to corticosteroid treatment is important to clinicians involved in the management of patients with inflammatory myopathies. © 2001 John Wiley & Sons, Inc. Muscle Nerve 24: 1562–1566, 2001