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Interruption of a relay of corticospinal excitation by a spinal lesion at C6–C7
Author(s) -
MarchandPauvert Véronique,
Mazevet Dominique,
PradatDiehl Pascale,
Alstermark Bror,
PierrotDeseilligny Emmanuel
Publication year - 2001
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.1183
Subject(s) - lesion , spinal cord , biceps , neuroscience , anatomy , electromyography , medicine , psychology , pathology
Abstract In a patient with a limited lesion of the spinal cord at the C6–C7 junction, ulnar and superficial radial‐induced modulations of the motor evoked potentials (MEP) and of ongoing electromyographic (EMG) activity were observed in the biceps (above the lesion) but not in the triceps (below the lesion). This suggests an interruption of the axons of cervical propriospinal neurons. This relay transmits an indirect (disynaptic) component of corticospinal excitation to human upper limb motoneurons. Changes in it might be involved in compensatory mechanisms following central motor disorders. © 2001 John Wiley & Sons, Inc. Muscle Nerve 24: 1554–1561, 2001