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McArdle's disease presenting as recurrent cryptogenic renal failure due to occult seizures
Author(s) -
Walker Adrianne R.,
Tschetter Kevin,
Matsuo Fumisuke,
Flanigan Kevin M.
Publication year - 2003
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.10463
Subject(s) - myoglobinuria , medicine , occult , cardiology , disease , pediatrics , rhabdomyolysis , pathology , alternative medicine
Myophosphorylase deficiency (McArdle's disease) may present with episodic renal failure following exertion. We present a case of adult‐onset myophosphorylase deficiency in which recurrent bouts of renal failure could not be associated with any exertional events until a tonic seizure was witnessed after the fourth episode of renal failure. In the absence of a clear exertional cause for myoglobinuria, an occult seizure disorder should be suspected. Muscle Nerve 28: 640–643, 2003