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Axonal pharyngeal‐cervical‐brachial variant of Guillain–Barré syndrome without Anti‐GT1a IgG antibody
Author(s) -
Arai Motomi,
Susuki Keiichiro,
Koga Michiaki
Publication year - 2003
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.10424
Subject(s) - guillain barre syndrome , medicine , antibody , pharynx , immunology , pathology , surgery
We report two cases of pharyngeal‐cervical‐brachial (PCB) variant of Guillain–Barré syndrome (GBS). The patients developed dysphagia and weakness of the neck and arms subsequent to Campylobacter jejuni infection. Oropharyngeal palsy recovered poorly. Electrophysiological findings demonstrated axonal conduction failure. Anti‐GD1a immunoglobulin G (IgG) antibody was detected in one case, and anti‐GM1b IgG antibody in another. Anti‐GT1a IgG and immunoglobulin M (IgM) antibodies were negative in both cases. The current cases suggest that the PCB and axonal variants of GBS form a continuous spectrum from the viewpoint of electrophysiological studies as well as antiganglioside serology. Muscle Nerve 28: 246–250, 2003