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Response to exercise of patients with idiopathic hyper‐CK‐emia
Author(s) -
Reijneveld J.C.,
Te Boekhorst B.C.M.,
Zonderland M.L.,
Kalmijn S.,
Notermans N.C.
Publication year - 2002
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.10232
Subject(s) - medicine , creatine kinase , physical exercise , exercise intolerance , cardiology , heart failure
Patients with an idiopathic increase in serum creatine kinase (CK) levels (hyper‐CK‐emia) have a benign prognosis, but symptoms may be disabling in daily life. Previous studies have suggested that physical exercise increases the severity of complaints in these patients. We studied whether maximal and submaximal bouts of exercise on a cycle ergometer are harmful for patients with idiopathic hyper‐CK‐emia. Such dynamic exercise did not lead to larger increases in serum CK activity or more complaints in 11 patients with idiopathic hyper‐CK‐emia, compared with 11 age‐matched healthy controls. Our data suggest that exercise does not result in more extensive muscle damage in patients with idiopathic hyper‐CK‐emia than in healthy subjects. © 2002 Wiley Periodicals, Inc. Muscle Nerve 26: 832–837, 2002