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Intravascular lymphomatosis
Author(s) -
Oei Melina E.,
Kraft George H.,
Sarnat Harvey B.
Publication year - 2002
Publication title -
muscle and nerve
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.025
H-Index - 145
eISSN - 1097-4598
pISSN - 0148-639X
DOI - 10.1002/mus.10091
Subject(s) - medicine , malignancy , lymphoma , polyneuropathy , concomitant , pathology , muscle biopsy , myopathy , autopsy , biopsy , chemotherapy
Intravascular lymphomatosis, also known as endovascular lymphoma or angiotropic large cell lymphoma, is a rare malignancy typically diagnosed at autopsy. We describe a case in which the diagnosis was made at an early stage. Specific electrodiagnostic findings suggested concomitant polyneuropathy and myopathy. Suspicion of a paraneoplastic syndrome during electrodiagnostic testing prompted muscle biopsy, which revealed myopathy due to the direct infiltration of neoplastic cells. Resultant treatment with a standard chemotherapy regimen not only increased the patient's survival, but also improved neurological function. © 2002 Wiley Periodicals, Inc. Muscle Nerve 25:000–000, 2002